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Hybridoma Passage In Vitro May Result in Reduced Ability of Antimannan Antibody To Protect against Disseminated Candidiasis

We previously reported the enhanced resistance of monoclonal antibodies B6.1 (an immunoglobulin M [IgM]) and C3.1 (an IgG3) against experimental candidiasis. Both MAbs recognize the same fungal epitope. We have since found that a highly passaged B6.1 hybridoma (hp-B6.1) resulted in antibody that has...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xin, Hong, Cutler, Jim E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489732/
https://ncbi.nlm.nih.gov/pubmed/16790805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00234-06
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