The First Histidine Triad Motif of PhtD Is Critical for Zinc Homeostasis in Streptococcus pneumoniae

Streptococcus pneumoniae is the world's foremost human pathogen. Acquisition of the first row transition metal ion zinc is essential for pneumococcal colonization and disease. Zinc is acquired via the ATP-binding cassette transporter AdcCB and two zinc-binding proteins, AdcA and AdcAII. We have...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Eijkelkamp, Bart A., Pederick, Victoria G., Plumptre, Charles D., Harvey, Richard M., Hughes, Catherine E., Paton, James C., McDevitt, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730578/
https://ncbi.nlm.nih.gov/pubmed/26573735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01082-15
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