WAC regulates mTOR activity by acting as an adaptor for the TTT and Pontin/Reptin complexes

The ability to sense energy status is crucial in the regulation of metabolism via the mechanistic Target of Rapamycin Complex 1 (mTORC1). The assembly of the TTT-Pontin/Reptin complex is responsive to changes in energy status. In energy sufficient conditions, the TTT-Pontin/Reptin complex promotes m...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: David-Morrison, Gabriela, Xu, Zhen, Rui, Yan-Ning, Charng, Wu-Lin, Jaiswal, Manish, Yamamoto, Shinya, Xiong, Bo, Zhang, Ke, Sandoval, Hector, Duraine, Lita, Zuo, Zhongyuan, Zhang, Sheng, Bellen, Hugo J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730548/
https://ncbi.nlm.nih.gov/pubmed/26812014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.12.019
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