Statin Therapy and the Development of Cerebral Amyloid Angiopathy—A Rodent in Vivo Approach

Background: Cerebral amyloid angiopathy (CAA) is characterized by vascular deposition of amyloid β (Aβ) with a higher incidence of cerebral microbleeds (cMBs) and spontaneous hemorrhage. Since statins are known for their benefit in vascular disease we tested for the effect on CAA. Methods: APP23-tra...

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Published in:Int J Mol Sci
Main Authors: Reuter, Björn, Venus, Alexander, Grudzenski, Saskia, Heiler, Patrick, Schad, Lothar, Staufenbiel, Matthias, Hennerici, Michael G., Fatar, Marc
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730367/
https://ncbi.nlm.nih.gov/pubmed/26797603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17010126
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