Benzobisthiazoles Represent a Novel Scaffold for Kinase Inhibitors of CLK Family Members

[Image: see text] Protein kinases are essential regulators of most cellular processes and are involved in the etiology and progression of multiple diseases. The cdc2-like kinases (CLKs) have been linked to various neurodegenerative disorders, metabolic regulation, and virus infection, and the kinase...

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Pubblicato in:Biochemistry
Autori principali: Prak, Krisna, Kriston-Vizi, Janos, Chan, A. W. Edith, Luft, Christin, Costa, Joana R., Pengo, Niccolo, Ketteler, Robin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730229/
https://ncbi.nlm.nih.gov/pubmed/26701387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01128
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