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Topical imiquimod yields systemic effects due to unintended oral uptake
Repetitive application of topical imiquimod is used as an experimental model for the induction of psoriasiform skin lesions in mice. The model is characterized by several inflammatory processes, including cytokine production both locally and systemically, cellular infiltration, and splenomegaly. To...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730190/ https://ncbi.nlm.nih.gov/pubmed/26818707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20134 |
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