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Interictal spikes during sleep are an early defect in the Tg2576 mouse model of β-amyloid neuropathology
It has been suggested that neuronal hyperexcitability contributes to Alzheimer’s disease (AD), so we asked how hyperexcitability develops in a common mouse model of β-amyloid neuropathology - Tg2576 mice. Using video-EEG recordings, we found synchronized, large amplitude potentials resembling interi...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730189/ https://ncbi.nlm.nih.gov/pubmed/26818394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20119 |
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