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An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels

Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias, cancer and trauma. To explore the mechanism by which Ca(2+) blocks intercellular communication during tissue injury, we determined the X-ray cr...

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發表在:Nat Commun
Main Authors: Bennett, Brad C., Purdy, Michael D., Baker, Kent A., Acharya, Chayan, McIntire, William E., Stevens, Raymond C., Zhang, Qinghai, Harris, Andrew L., Abagyan, Ruben, Yeager, Mark
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730032/
https://ncbi.nlm.nih.gov/pubmed/26753910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9770
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