An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels

Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias, cancer and trauma. To explore the mechanism by which Ca(2+) blocks intercellular communication during tissue injury, we determined the X-ray cr...

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Опубликовано в: :Nat Commun
Главные авторы: Bennett, Brad C., Purdy, Michael D., Baker, Kent A., Acharya, Chayan, McIntire, William E., Stevens, Raymond C., Zhang, Qinghai, Harris, Andrew L., Abagyan, Ruben, Yeager, Mark
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730032/
https://ncbi.nlm.nih.gov/pubmed/26753910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9770
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