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The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

Autophagosomes are double-membrane vesicles that sequester cytoplasmic material for lysosomal degradation. Their biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. This process depends on the regulated activation of the Atg1–kinase complex. However, the underlyi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rao, Yijian, Perna, Marco G., Hofmann, Benjamin, Beier, Viola, Wollert, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729957/
https://ncbi.nlm.nih.gov/pubmed/26753620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10338
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