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TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis

Cytoplasmic stress granules (SGs) are multimolecular aggregates of stalled translation pre-initiation complexes that prevent the accumulation of misfolded proteins, and that are formed in response to certain types of stress including ER stress. SG formation contributes to cell survival not only by s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Arimoto-Matsuzaki, Kyoko, Saito, Haruo, Takekawa, Mutsuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729832/
https://ncbi.nlm.nih.gov/pubmed/26738979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10252
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