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TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis

Cytoplasmic stress granules (SGs) are multimolecular aggregates of stalled translation pre-initiation complexes that prevent the accumulation of misfolded proteins, and that are formed in response to certain types of stress including ER stress. SG formation contributes to cell survival not only by s...

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Publicado en:Nat Commun
Autores principales: Arimoto-Matsuzaki, Kyoko, Saito, Haruo, Takekawa, Mutsuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729832/
https://ncbi.nlm.nih.gov/pubmed/26738979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10252
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