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Nanopore-Based Conformational Analysis of a Viral RNA Drug Target

[Image: see text] Nanopores are single-molecule sensors that show exceptional promise as a biomolecular analysis tool by enabling label-free detection of small amounts of sample. In this paper, we demonstrate that nanopores are capable of detecting the conformation of an antiviral RNA drug target. T...

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Detalles Bibliográficos
Publicado en:ACS Nano
Autores principales: Shasha, Carolyn, Henley, Robert Y., Stoloff, Daniel H., Rynearson, Kevin D., Hermann, Thomas, Wanunu, Meni
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729693/
https://ncbi.nlm.nih.gov/pubmed/24861167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn501969r
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