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Length-Independent DNA Packing into Nanopore Zero-Mode Waveguides for Low-Input DNA Sequencing

Compared to conventional methods, single molecule, real-time (SMRT) DNA sequencing exhibits longer read lengths than conventional methods, less GC per cent bias, and the ability to read DNA base modifications. However, reading DNA sequence from sub-ng quantities is impractical due to inefficient del...

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Detalhes bibliográficos
Publicado no:Nat Nanotechnol
Main Authors: Larkin, Joseph, Henley, Robert Y., Jadhav, Vivek, Korlach, Jonas, Wanunu, Meni
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718969/
https://ncbi.nlm.nih.gov/pubmed/28892102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2017.176
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