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Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development
Early mouse development is accompanied by dynamic changes in chromatin modifications, including G9a-mediated histone H3 lysine 9 dimethylation (H3K9me2), which is essential for embryonic development. Here we show that genome-wide accumulation of H3K9me2 is crucial for postimplantation development, a...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4729692/ https://ncbi.nlm.nih.gov/pubmed/26551560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09571 |
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