A neutral polydisulfide containing Gd(III) DOTA monoamide as a redox-sensitive biodegradable macromolecular MRI contrast agent

This work aims to develop safe and effective gadolinium (III)-based biodegradable macromolecular MRI contrast agents for blood pool and cancer imaging. A neutral polydisulfide containing macrocyclic Gd-DOTA monoamide (GOLS) was synthesized and characterized. In addition to studying the in vitro degr...

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Publicado en:Contrast Media Mol Imaging
Autores principales: Ye, Zhen, Zhou, Zhuxian, Ayat, Nadia, Wu, Xueming, Jin, Erlei, Shi, Xiaoyue, Lu, Zheng-Rong
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729617/
https://ncbi.nlm.nih.gov/pubmed/26218648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.1655
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