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In Vivo and Ex Vivo Regulation of Breast Cancer Resistant Protein (Bcrp) by Peroxisome Proliferator-Activated Receptor Alpha (Pparα) at the Blood-Brain Barrier
Breast cancer resistance protein (Bcrp/Abcg2) localized at the blood-brain barrier (BBB) limits permeability into the brain of many xenobiotics, including pharmacological agents. Peroxisome proliferator-activated receptor α (Pparα), a ligand-activated transcription factor, primarily involved in lipi...
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| Gepubliceerd in: | J Neurochem |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4729455/ https://ncbi.nlm.nih.gov/pubmed/26465636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13389 |
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