Problems of variable biomarker evaluation in stratified medicine research—A case study of ERCC1 in non-small-cell lung cancer

OBJECTIVES: Consistency of procedures for the evaluation of a predictive biomarker (including sample collection, processing, assay and scoring system) based on adequate evidence is necessary to implement research findings in clinical practice. As a case study we evaluated how a particular predictive...

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Udgivet i:Lung Cancer
Main Authors: Malottki, Kinga, Popat, Sanjay, Deeks, Jonathan J., Riley, Richard D., Nicholson, Andrew G., Billingham, Lucinda
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Scientific Publishers 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729317/
https://ncbi.nlm.nih.gov/pubmed/26775588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2015.11.017
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