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Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers

OBJECTIVES: Stratified medicine is often heralded as the future of clinical practice. Key part of stratified medicine is the use of predictive biomarkers, which identify patient subgroups most likely to benefit (or least likely to experience harm) from an intervention. We investigated how many and w...

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Detalhes bibliográficos
Main Authors: Malottki, Kinga, Biswas, Mousumi, Deeks, Jonathan J, Riley, Richard D, Craddock, Charles, Johnson, Philip, Billingham, Lucinda
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913033/
https://ncbi.nlm.nih.gov/pubmed/24468721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2013-004188
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