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Stratified medicine in European Medicines Agency licensing: a systematic review of predictive biomarkers

OBJECTIVES: Stratified medicine is often heralded as the future of clinical practice. Key part of stratified medicine is the use of predictive biomarkers, which identify patient subgroups most likely to benefit (or least likely to experience harm) from an intervention. We investigated how many and w...

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Hlavní autoři: Malottki, Kinga, Biswas, Mousumi, Deeks, Jonathan J, Riley, Richard D, Craddock, Charles, Johnson, Philip, Billingham, Lucinda
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913033/
https://ncbi.nlm.nih.gov/pubmed/24468721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2013-004188
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