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HIF-1α siRNA reduces retinal neovascularization in a mouse model of retinopathy of prematurity

OBJECTIVE: To explore the effect of HIF-1α specific siRNA expression vector pSUPERH1-siHIF-1α on retinal neovascularization in a mouse model of retinopathy of prematurity (ROP). METHODS: Forty-eight newborn C57BL/6J mice were randomly divided into the control and experimental groups (n=24 apiece) to...

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Detalhes bibliográficos
Publicado no:Transl Pediatr
Main Authors: Xu, Hui-Zhuo, Liu, Shuang-Zhen, Xiong, Si-Qi, Xia, Xiao-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728947/
https://ncbi.nlm.nih.gov/pubmed/26835279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2224-4336.2012.03.01
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