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Suppression of Retinal Neovascularization by Erythropoietin siRNA in a Mouse Model of Proliferative Retinopathy

PURPOSE: Erythropoietin (EPO), an oxygen-regulated hormone stimulating erythrocyte production, was recently found to be critical for retinal angiogenesis. EPO mRNA expression levels in retina are highly elevated during the hypoxia-induced proliferation phase of retinopathy. The authors investigated...

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Detalhes bibliográficos
Main Authors: Chen, Jing, Connor, Kip M., Aderman, Christopher M., Willett, Keirnan L., Aspegren, Oskar P., Smith, Lois E. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892257/
https://ncbi.nlm.nih.gov/pubmed/18952918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2521
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