The interaction between artemether-lumefantrine and lopinavir/ritonavir-based antiretroviral therapy in HIV-1 infected patients

BACKGROUND: Artemether-lumefantrine is currently the most widely recommended treatment of uncomplicated malaria. Lopinavir–based antiretroviral therapy is the commonly recommended second-line HIV treatment. Artemether and lumefantrine are metabolised by cytochrome P450 isoenzyme CYP3A4, which lopina...

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Udgivet i:BMC Infect Dis
Main Authors: Kredo, T., Mauff, K., Workman, L., Van der Walt, J. S., Wiesner, L., Smith, P. J., Maartens, G., Cohen, K., Barnes, K. I.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728832/
https://ncbi.nlm.nih.gov/pubmed/26818566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1345-1
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