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Integrin-mediated resistance to epidermal growth factor receptor-targeted therapy: an inflammatory situation

Targeting the function of epidermal growth factor receptor (EGFR) has failed as an effective clinical option for breast cancer. Understanding the drivers of inherent resistance has been a challenge. One possible mechanism is the acquisition of stem-like properties through the process of epithelial-m...

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Publicat a:Breast Cancer Res
Autors principals: Brown, Wells S, Wendt, Michael K
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728772/
https://ncbi.nlm.nih.gov/pubmed/25255930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0448-0
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