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Targeting the epidermal growth factor receptor

The epidermal growth factor receptor (EGFR) is a member of the erbB family of tyrosine kinase receptors (RTK). The EGFR is involved in cell proliferation, metastasis and angiogenesis, and is expressed in a large proportion of epithelial tumours. The two main classes of EGFR inhibitors in clinical tr...

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Detalhes bibliográficos
Main Authors: El-Rayes, B F, LoRusso, P M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409851/
https://ncbi.nlm.nih.gov/pubmed/15238978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601921
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