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Precision Medicine: Genetic Repair of Retinitis Pigmentosa in Patient-Derived Stem Cells

Induced pluripotent stem cells (iPSCs) generated from patient fibroblasts could potentially be used as a source of autologous cells for transplantation in retinal disease. Patient-derived iPSCs, however, would still harbor disease-causing mutations. To generate healthy patient-derived cells, mutatio...

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Опубликовано в: :Sci Rep
Главные авторы: Bassuk, Alexander G., Zheng, Andrew, Li, Yao, Tsang, Stephen H., Mahajan, Vinit B.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728485/
https://ncbi.nlm.nih.gov/pubmed/26814166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19969
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