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Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects

Endoglin overexpression is associated with highly proliferative tumor endothelium and also with some tumors, including melanoma. Its targeting has anti-tumor effectiveness, which can also be obtained by RNA interference. The aim of our study was to explore the anti-tumor effectiveness of endoglin si...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Dolinsek, Tanja, Sersa, Gregor, Prosen, Lara, Bosnjak, Masa, Stimac, Monika, Razborsek, Urska, Cemazar, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728450/
https://ncbi.nlm.nih.gov/pubmed/26712792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8010003
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