Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores

During metaphase, forces on kinetochores are exerted by k-fibres, bundles of microtubules that end at the kinetochore. Interestingly, non-kinetochore microtubules have been observed between sister kinetochores, but their function is unknown. Here we show by laser-cutting of a k-fibre in HeLa and PtK...

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Udgivet i:Nat Commun
Main Authors: Kajtez, Janko, Solomatina, Anastasia, Novak, Maja, Polak, Bruno, Vukušić, Kruno, Rüdiger, Jonas, Cojoc, Gheorghe, Milas, Ana, Šumanovac Šestak, Ivana, Risteski, Patrik, Tavano, Federica, Klemm, Anna H., Roscioli, Emanuele, Welburn, Julie, Cimini, Daniela, Glunčić, Matko, Pavin, Nenad, Tolić, Iva M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728446/
https://ncbi.nlm.nih.gov/pubmed/26728792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10298
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