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Detecting the Common and Individual Effects of Rare Variants on Quantitative Traits by Using Extreme Phenotype Sampling

Next-generation sequencing technology has made it possible to detect rare genetic variants associated with complex human traits. In recent literature, various methods specifically designed for rare variants are proposed. These tests can be broadly classified into burden and nonburden tests. In this...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Zhou, Ya-Jing, Wang, Yong, Chen, Li-Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728382/
https://ncbi.nlm.nih.gov/pubmed/26784232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7010002
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