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There are four dynamically and functionally distinct populations of E-cadherin in cell junctions

E-cadherin is a trans-membrane tumor suppressor responsible for epithelial cell adhesion. E-cadherin forms adhesive clusters through combined extra-cellular cis- and trans-interactions and intracellular interaction with the actin cytoskeleton. Here we identify four populations of E-cadherin within c...

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Détails bibliographiques
Publié dans:Biol Open
Auteurs principaux: Erami, Zahra, Timpson, Paul, Yao, Wu, Zaidel-Bar, Ronen, Anderson, Kurt I.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728362/
https://ncbi.nlm.nih.gov/pubmed/26471767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.014159
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