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Sustained α-catenin Activation at E-cadherin Junctions in the Absence of Mechanical Force
Mechanotransduction at E-cadherin junctions has been postulated to be mediated in part by a force-dependent conformational activation of α-catenin. Activation of α-catenin allows it to interact with vinculin in addition to F-actin, resulting in a strengthening of junctions. Here, using E-cadherin ad...
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| Udgivet i: | Biophys J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018127/ https://ncbi.nlm.nih.gov/pubmed/27602732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.06.027 |
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