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Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts
Oxidative stress in cardiac fibroblasts (CFs) promotes transformation to myofibroblasts and collagen synthesis leading to myocardial fibrosis, a precursor to heart failure (HF). NADPH oxidase 4 (Nox4) is a major source of cardiac reactive oxygen species (ROS); however, mechanisms of Nox4 regulation...
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| Publicado no: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728312/ https://ncbi.nlm.nih.gov/pubmed/26449263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019968 |
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