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PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility
Cell contractility and migration by integrins depends on precise regulation of protein tyrosine kinase and Rho-family GTPase activities in specific spatiotemporal patterns. Here we show that protein tyrosine phosphatase PTP1B cooperates with β3 integrin to activate the Src/FAK signalling pathway whi...
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| Udgivet i: | Biol Open |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4728310/ https://ncbi.nlm.nih.gov/pubmed/26700725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.015883 |
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