PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility

Cell contractility and migration by integrins depends on precise regulation of protein tyrosine kinase and Rho-family GTPase activities in specific spatiotemporal patterns. Here we show that protein tyrosine phosphatase PTP1B cooperates with β3 integrin to activate the Src/FAK signalling pathway whi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biol Open
Egile Nagusiak: González Wusener, Ana E., González, Ángela, Nakamura, Fumihiko, Arregui, Carlos O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728310/
https://ncbi.nlm.nih.gov/pubmed/26700725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.015883
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