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Effects of retinoic acid on proliferation, phenotype and expression of cyclin-dependent kinase inhibitors in TGF-β1-stimulated rat hepatic stellate cells

AIM: To study the molecular mechanisms of retinoic acid (RA) on proliferation and expression of cyclin-dependent kinase inhibitors (CKI), i.e. p16, p21 and p27 in cultured rat hepatic stellate cells (HSC) stimulated with transforming growth factor beta 1 (TGF-β1). METHODS: HSC were isolated from hea...

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Publicat a:World J Gastroenterol
Autors principals: Huang, Guang Cun, Zhang, Jin Sheng, Zhang, Yue E
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728268/
https://ncbi.nlm.nih.gov/pubmed/11819702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v6.i6.819
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