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Synthesis and Characterization of Impurities in the Production Process of Lopinavir

Lopinavir is an antiretroviral drug used for the inhibition of HIV protease. Four related substances of lopinavir were observed during the manufacturing process of lopinavir in the laboratory and they were identified. The present work describes the origin, synthesis, characterization, and control of...

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Publicat a:Sci Pharm
Autors principals: Raghava Reddy, Ambati V., Garaga, Srinivas, Takshinamoorthy, Chandiran, Naidu, Andra
Format: Artigo
Idioma:Inglês
Publicat: The Austrian Journal of Pharmaceutical Sciences 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727799/
https://ncbi.nlm.nih.gov/pubmed/26839801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1407-14
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