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Influence of Ethanol as a Co-Solvent in Cyclodextrin Inclusion Complexation: A Molecular Dynamics Study

Molecular dynamics (MD) simulations were used to investigate the dynamics and host-guest interactions of the inclusion complexes between a potent anti-HIV agent, UC781, and three different types of cyclodextrins (CDs) including βCD, 2,6-dimethyl-βCD (MβCD), and 2-hydroxypropyl-βCD (HPβCD) in aqueous...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Pharm
Hauptverfasser: Boonyarattanakalin, Kanokthip, Viernstein, Helmut, Wolschann, Peter, Lawtrakul, Luckhana
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Austrian Journal of Pharmaceutical Sciences 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727776/
https://ncbi.nlm.nih.gov/pubmed/26839825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1412-08
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