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Inhibition of 12/15-Lipoxygenase Reduces Renal Inflammation and Injury in Streptozotocin-Induced Diabetic Mice

Previous studies suggest that 12/15 lipoxygenase (12/15-LO) is implicated in diabetic vascular complications. We hypothesize that 12/15-LO inhibition attenuates renal inflammation and injury in streptozotocin-induced diabetes. Diabetes was induced in wild-type C57BL/6J (WT) and 12/15-LO deficient mi...

詳細記述

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書誌詳細
出版年:J Diabetes Metab
主要な著者: Faulkner, Jessica, Pye, Chelsey, Al-Shabrawey, Mohamed, Elmarakby, Ahmed A
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727755/
https://ncbi.nlm.nih.gov/pubmed/26823989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6156.1000555
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