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Inhibition of 12/15-Lipoxygenase Reduces Renal Inflammation and Injury in Streptozotocin-Induced Diabetic Mice

Previous studies suggest that 12/15 lipoxygenase (12/15-LO) is implicated in diabetic vascular complications. We hypothesize that 12/15-LO inhibition attenuates renal inflammation and injury in streptozotocin-induced diabetes. Diabetes was induced in wild-type C57BL/6J (WT) and 12/15-LO deficient mi...

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Bibliographic Details
Published in:J Diabetes Metab
Main Authors: Faulkner, Jessica, Pye, Chelsey, Al-Shabrawey, Mohamed, Elmarakby, Ahmed A
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727755/
https://ncbi.nlm.nih.gov/pubmed/26823989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6156.1000555
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