Imiquimod‐induced apoptosis of melanoma cells is mediated by ER stress‐dependent Noxa induction and enhanced by NF‐κB inhibition

Melanoma is characterized by dysregulated intracellular signalling pathways including an impairment of the cell death machinery, ultimately resulting in melanoma resistance, survival and progression. This explains the tumour's extraordinary resistance to the standard treatment. Imiquimod is a t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Mol Med
Egile Nagusiak: El‐Khattouti, Abdelouahid, Selimovic, Denis, Hannig, Matthias, Taylor, Erin B., Abd Elmageed, Zakaria Y., Hassan, Sofie Y., Haikel, Youssef, Kandil, Emad, Leverkus, Martin, Brodell, Robert T., Megahed, Mosaad, Hassan, Mohamed
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2015
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727561/
https://ncbi.nlm.nih.gov/pubmed/26578344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12718
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