Imiquimod‐induced apoptosis of melanoma cells is mediated by ER stress‐dependent Noxa induction and enhanced by NF‐κB inhibition

Melanoma is characterized by dysregulated intracellular signalling pathways including an impairment of the cell death machinery, ultimately resulting in melanoma resistance, survival and progression. This explains the tumour's extraordinary resistance to the standard treatment. Imiquimod is a t...

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Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: El‐Khattouti, Abdelouahid, Selimovic, Denis, Hannig, Matthias, Taylor, Erin B., Abd Elmageed, Zakaria Y., Hassan, Sofie Y., Haikel, Youssef, Kandil, Emad, Leverkus, Martin, Brodell, Robert T., Megahed, Mosaad, Hassan, Mohamed
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2015
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727561/
https://ncbi.nlm.nih.gov/pubmed/26578344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12718
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