Imiquimod‐induced apoptosis of melanoma cells is mediated by ER stress‐dependent Noxa induction and enhanced by NF‐κB inhibition

Melanoma is characterized by dysregulated intracellular signalling pathways including an impairment of the cell death machinery, ultimately resulting in melanoma resistance, survival and progression. This explains the tumour's extraordinary resistance to the standard treatment. Imiquimod is a t...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Cell Mol Med
Hlavní autoři: El‐Khattouti, Abdelouahid, Selimovic, Denis, Hannig, Matthias, Taylor, Erin B., Abd Elmageed, Zakaria Y., Hassan, Sofie Y., Haikel, Youssef, Kandil, Emad, Leverkus, Martin, Brodell, Robert T., Megahed, Mosaad, Hassan, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727561/
https://ncbi.nlm.nih.gov/pubmed/26578344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12718
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky