Saw1 Localizes to Repair Sites but is not Required for Recruitment of Rad10 to Repair Intermediates Bearing Short Non-Homologous 3′ Flaps during Single-Strand Annealing in S. cerevisiae

SAW1 is required for efficient removal by the Rad1-Rad10 nuclease of 3′ non-homologous DNA ends (flaps) formed as intermediates during two modes of double-strand break repair in S. cerevisiae, single-strand annealing (SSA) and synthesis-dependent strand annealing (SDSA). Saw1 was shown in vitro to b...

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Vydáno v:Mol Cell Biochem
Hlavní autoři: Mardirosian, Melina, Nalbandyan, Linette, Miller, Aaron D., Phan, Claire, Kelson, Eric P., Fischhaber, Paula L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727451/
https://ncbi.nlm.nih.gov/pubmed/26699908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-015-2616-7
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