Association of NMT2 with the acyl-CoA carrier ACBD6 protects the N-myristoyltransferase reaction from palmitoyl-CoA

The covalent attachment of a 14-carbon aliphatic tail on a glycine residue of nascent translated peptide chains is catalyzed in human cells by two N-myristoyltransferase (NMT) enzymes using the rare myristoyl-CoA (C(14)-CoA) molecule as fatty acid donor. Although, NMT enzymes can only transfer a myr...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Soupene, Eric, Kao, Joseph, Cheng, Daniel H., Wang, Derek, Greninger, Alexander L., Knudsen, Giselle M., DeRisi, Joseph L., Kuypers, Frans A.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727424/
https://ncbi.nlm.nih.gov/pubmed/26621918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M065003
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