Secretion of a single-gene-encoded immunoglobulin from myeloma cells.

We describe construction of a single gene encoding a single-chain immunoglobulin-like molecule. This single-gene approach circumvents inefficiencies inherent in delivering two genes into a mammalian cell and in the assembly of a functional immunoglobulin molecule. It would also facilitate ex vivo tr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Shu, L, Qi, C F, Schlom, J, Kashmiri, S V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8367454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.7995
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