Secretion of a single-gene-encoded immunoglobulin from myeloma cells.
We describe construction of a single gene encoding a single-chain immunoglobulin-like molecule. This single-gene approach circumvents inefficiencies inherent in delivering two genes into a mammalian cell and in the assembly of a functional immunoglobulin molecule. It would also facilitate ex vivo tr...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1993
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8367454/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.17.7995 |
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