Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells

BACKGROUND: Clinical observations indicate that the presence of nucleus pulposus (NP) tissue during spinal fusion hinders the rate of disc ossification. While the underlying mechanism remains unknown, this observation could be due to incomplete removal of NP cells (NPCs) that secrete factors prevent...

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Publicado en:Arthritis Res Ther
Autores principales: Chan, Samantha C. W., Tekari, Adel, Benneker, Lorin M., Heini, Paul F., Gantenbein, Benjamin
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727301/
https://ncbi.nlm.nih.gov/pubmed/26809343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0900-2
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