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Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells

BACKGROUND: Clinical observations indicate that the presence of nucleus pulposus (NP) tissue during spinal fusion hinders the rate of disc ossification. While the underlying mechanism remains unknown, this observation could be due to incomplete removal of NP cells (NPCs) that secrete factors prevent...

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Pubblicato in:Arthritis Res Ther
Autori principali: Chan, Samantha C. W., Tekari, Adel, Benneker, Lorin M., Heini, Paul F., Gantenbein, Benjamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727301/
https://ncbi.nlm.nih.gov/pubmed/26809343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0900-2
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