Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells

BACKGROUND: Clinical observations indicate that the presence of nucleus pulposus (NP) tissue during spinal fusion hinders the rate of disc ossification. While the underlying mechanism remains unknown, this observation could be due to incomplete removal of NP cells (NPCs) that secrete factors prevent...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Chan, Samantha C. W., Tekari, Adel, Benneker, Lorin M., Heini, Paul F., Gantenbein, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727301/
https://ncbi.nlm.nih.gov/pubmed/26809343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0900-2
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