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Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells

BACKGROUND: Clinical observations indicate that the presence of nucleus pulposus (NP) tissue during spinal fusion hinders the rate of disc ossification. While the underlying mechanism remains unknown, this observation could be due to incomplete removal of NP cells (NPCs) that secrete factors prevent...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Chan, Samantha C. W., Tekari, Adel, Benneker, Lorin M., Heini, Paul F., Gantenbein, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727301/
https://ncbi.nlm.nih.gov/pubmed/26809343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0900-2
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