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Regulation of miR-200c/141 expression by intergenic DNA-looping and transcriptional read-through
The miR-200 family members have been implicated in stress responses and ovarian tumorigenesis. Here, we find that miR-200c/141 transcription is intimately linked to the transcription of the proximal upstream gene PTPN6 (SHP1) in all physiological conditions tested. PTPN6 and miR-200c/141 are transcr...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4727242/ https://ncbi.nlm.nih.gov/pubmed/26725650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9959 |
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