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Protoporphyrin IX: the Good, the Bad, and the Ugly

Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme. PPIX has some biologic functions of its own, and PPIX-based strategies have been used for cancer diagnosis and treatment (the good). PPIX serves as the substrate for ferrochelatase, the fina...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Sachar, Madhav, Anderson, Karl E., Ma, Xiaochao
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727154/
https://ncbi.nlm.nih.gov/pubmed/26588930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.228130
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