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Overexpression of MCPH1 inhibits uncontrolled cell growth by promoting cell apoptosis and arresting the cell cycle in S and G2/M phase in lung cancer cells

Microcephalin (MCPH1/BRIT1) is a large nuclear protein that is involved in the early cellular response to DNA damage, the expression of which is reduced in a variety of types of human tumors. A recent study by our group demonstrated that MCPH1 expression is markedly decreased in lung cancer. However...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: ZHOU, LIMIN, BAI, YANJIE, LI, YANXI, LIU, XUELIANG, TAN, TAO, MENG, SHASHA, HE, WENTING, WU, XIAOBIN, DONG, ZHIFANG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727150/
https://ncbi.nlm.nih.gov/pubmed/26870219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3857
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